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Violation Code: 27

FDA Violation

Charge Code: DRUG GMPS

3,954
Total Refusals
834
Affected Firms
12/29/2025
Latest Case
10/3/2001
First Case

Violation Details

Violation Code (ASC ID)
27
Charge Code
DRUG GMPS
Description
The article is subject to refusal of admission pursuant to Section 801(a)(3) in that the methods used in and controls used for the manufacture, processing, packing, or holding of drugs and other products do not appear to conform to current good manufacturing practices within the meaning of Section 501(a)(2)(B).
Legal Section
501(a)(2)(B), 801(a)(3); ADULTERATION

Most Affected Firms

#Firm NameLocationCases
1Emcure Pharmaceuticals LimitedPune, INDIA167
2Aplicare Products, LLCMeriden, UNITED STA158
3SANUM-Kehlbeck GmbH & Co. KGHoya, GERMANY151
44E Global, S.A.P.I. de C.V.Tultitlan De Mariano Escobedo, MEXICO133
5Apollo Health And Beauty Care, Inc.North York, CANADA110
6Sun Pharmaceutical Industries Ltd.Halol, INDIA108
7Germiphene CorporationBrantford, CANADA86
8Kolmar Korea Co., Ltd. - Gwanjeong FactoryChungcheongnam-Do, SOUTH KORE81
9Casmara Cosmetics, S.A.Paterna, SPAIN78
10Tan-Alize Kozmetik ve Temizlik Urunleri Sanayi ve Ticaret A.S.Cekmekoy, TURKEY74
11Rxhomeo Private LimitedHyderabad, INDIA56
12Zobele De Mexico Sa De CvHermosillo, MEXICO53
13Herbion Pakistan (Pvt.) Ltd.Karachi, PAKISTAN46
14Apotex, Inc.Etobicoke, CANADA46
15Kolmar Korea Co. Ltd.Sejong, SOUTH KORE42
16Cosmecca Korea Co., Ltd.Eumseong, SOUTH KORE39
17Intas Pharmaceuticals LimitedAhmedabad, INDIA38
18Glenmark Pharmaceuticals LimitedSolan, INDIA38
19Opto-Pharm Pte Ltd.Singapore, SINGAPORE34
20Lernapharm (Loris) Inc.Saint-Laurent, CANADA33

Recent Import Refusals

DateProductFirm
12/29/2025
PHARMACEUTIC NECESSITIES AND CONTAINERS, N.E.C.
55YP99
12/29/2025
CLOPIDOGREL BISULFATE (ANTI-COAGULANT)
61LDC38
12/29/2025
ANTIFUNGAL N.E.C.
56GAC99
12/22/2025
ANTI-HYPERTENSIVE N.E.C.
62CDA99
12/19/2025
FLUOXETINE (ANTI-DEPRESSANT)
61NDY29
12/19/2025
ARIPIPRAZOLE (TRANQUILIZER (ANTI-PSYCHOTIC) - PART II)
66NDY06
12/19/2025
ULTRAVIOLET SCREEN/SUNSCREEN N.E.C.
66PAY99
12/19/2025
LEVONORGESTREL (ESTROGEN)
64GDA29
12/12/2025
LEVOCARNITINE (NUTRIENT/TONIC)
65CDY07
12/8/2025
ASHWAGANDHA (HERBAL & BOTANICALS, NOT TEAS)
54FGF94
12/5/2025
GUAIFENESIN (EXPECTORANT)
64HDY02
11/25/2025
TOBRAMYCIN (ANTI-MICROBIAL)
62HDY02
11/25/2025
CARBOXYMETHYLCELLULOSE SODIUM, EMOLLIENT,LUBRICANT
64DDY01
11/19/2025
HOMEOPATHIC ANALGESIC
66XBL01
11/19/2025
HOMEOPATHIC ANALGESIC
66XBL01

Related Violations

Other violations under the same legal section: 501(a)(2)(B), 801(a)(3); ADULTERATION

CodeCharge CodeCases
3847FDF4APIGMP43
339TAMPERING14

Frequently Asked Questions

What is FDA violation code 27?

27 is an FDA violation code that indicates: "The article is subject to refusal of admission pursuant to Section 801(a)(3) in that the methods used in and controls used for the manufacture, processing, packing, or holding of drugs and other products do not appear to conform to current good manufacturing practices within the meaning of Section 501(a)(2)(B).". This violation is based on 501(a)(2)(B), 801(a)(3); ADULTERATION of the Federal Food, Drug, and Cosmetic Act.

How many import refusals have been issued for violation 27?

According to FDA Import Refusal data, there have been 3954 import refusals issued for violation code 27, affecting 834 unique firms.

When was the most recent refusal for violation 27?

The most recent import refusal for violation 27 was on December 29, 2025.

What products are commonly refused for violation 27?

Products commonly refused under violation 27 include: PHARMACEUTIC NECESSITIES AND CONTAINERS, N.E.C., CLOPIDOGREL BISULFATE (ANTI-COAGULANT), ANTIFUNGAL N.E.C., ANTI-HYPERTENSIVE N.E.C., FLUOXETINE (ANTI-DEPRESSANT). These products were refused entry because they did not meet FDA requirements.

What is the legal basis for FDA violation code 27?

Violation code 27 is based on 501(a)(2)(B), 801(a)(3); ADULTERATION of the Federal Food, Drug, and Cosmetic Act (FD&C Act). This section of the law establishes requirements that imported products must meet to be allowed entry into the United States.

Data sourced from the FDA Data Dashboard, a public database maintained by the U.S. Food and Drug Administration.